汪丽韡,张必嘏

• 1:上海市第一人民医院宝山分院

摘要(Abstract)：

目的观察参芪扶正注射液对慢性充血性心力衰竭(CHF)患者心功能、脑钠肽(BNP)和心肌肌钙蛋白Ⅰ(cTnⅠ)的影响。方法 240例CHF患者随机分为观察组和对照组,每组120例。对照组予以常规治疗,观察组在对照组的基础上予以参芪扶正注射液治疗。观察治疗前和治疗后12 d 2组左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、左室射血分数(LVEF),BNP,cTnⅠ和6 min步行试验(6MWT)的变化及治疗后的疗效。结果对照组总有效率为75.00%,观察组总有效率为86.67%,观察组的疗效明显优于对照组(2=4.545,P<0.05)。观察组治疗后LVEDD,LVESD,BNP和cTnⅠ水平较对照组明显降低(P均<0.01),而LVEF和6MWT水平较对照组明显升高(P均<0.01)。结论在常规治疗基础上加用参芪扶正注射液,能提高对CHF的治疗效果,降低BNP和cTnⅠ水平,改善心功能。

关键词(KeyWords)： 参芪扶正注射液;充血性心力衰竭;心功能;脑钠肽;肌钙蛋白Ⅰ

Abstract:

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基金项目(Foundation):

作者(Author): 汪丽韡,张必嘏

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